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Evaluation of bacterial profile, antibiotic susceptibility patterns


Saiful Alam SK.1 Chowdhury MH.2 Naser MJA 3 Shamsuzzaman SM.4


Background: In ICU, catheter associated urinary tract infections (CA-UTI) are considered as principal threats to patient’s health and are the leading cause of morbidity and mortality. It is superimposed by the emergence of multi drug resistant (MDR) organisms which ultimately leads to social and economic burden on the community. Methodology: Samples were collected from clinically suspected patients of CA-UTI in ICU. Sample screening, bacterial isolation and antibiotic susceptibility were done by standard procedures. Quinolone, colistin, imipenem and tigecycline resistance genes were identified by PCR. Result: One hundred fifty urine samples were taken from clinically suspected CA-UTI patients of ICU. CA-UTI was found in 72 (48%) after standard primary screening. Among the common pathogens 30 (41.67%) were E. coli, 20 (27.78%) were Pseudomonas spp., 13 (18.05%) were Klebsiella spp., and 1 (1.38%) coagulase negative Staphylococcus (CoNS) were found. In this study, colistin showed the best sensitivity while ceftriaxone, ciprofloxacin amoxiclav and gentamicin were not promising against the isolated organisms causing CA-UTI in ICU of DMCH. Conclusion: The high proportions of CA-UTI in ICU highlights the need of regular antimicrobial  surveillance program to prevent emergence of multi drug resistant (MDR) organisms.

Issue: Vol. 6 No. 1 (2020)

Publish Date: Jun 06, 2022