Naher M1, Billah A2, Sultan R3, Jabbar T.S4, Urmi S.J5, Dolon F6, Sultana J7’
Objective: The aim of the study was to find out the effectiveness of per-rectal Misoprostol in the prevention of post-partum hemorrhage and to compare the effectiveness between per-rectal Misoprostol and intramuscular Oxytocin. Materials and Methods: This comparative prospective study was conducted in the Department of obstetrics and gynecology of Sir Salimullah Medical College & Mitford Hospital (SSME & MH) during the period of January 2016 to December 2016. One hundred pregnant patients were admitted in the labour ward having third stage of labour included population for this study. In group I (50 patients) received 600 ugm per-rec- tal Misoprostol after the delivery of baby. In group II (50 patients) received intramuscular 10 LU. Oxytocin at 3rd stage of labour. The outcome measured by collecting information of duration of stage, amount of blood loss, comparison of change in hemoglobin level, blood transfusion required and cause of P.P.H. Results: It was found that cause of P.P.H in both groups are retained placenta, genital trauma and uterine atony. Most of the patients had anemia in both groups. The mean amount of Postpartum bleeding was 42.6420.8 ml (£SD) in group I and 34,5+35.2 ml (+SD) in group II. No patient of group I required blood transfusion but 10% patient from group II required blood transfusion. There was no serious morbidity and bleeding was controlled effectively all the cases. Conclusion: This procedure is very safe, easy, cheap & does not require any logistic support. Routine use of Misoprostol analogue 600 gm effective in blood loss after delivery. The study recommends the regimen for 100 resources, busy obstetric settings.
Key words: Postpartum hemorrhage, Per-rectal, Misoprostel, Prophylaxis Oxytocin.